Eye Drop API

• Appearance
• White to off-white powder

• CAS No
• 155206-00-1

• Chemical Name
• Bimatoprost

• Color
• Other, White to off-white

• Grade
• Other, Pharmaceutical Grade

• HS Code
• 29322090

• Heavy Metal (%)
• NMT 0.001%

• Loss on Drying
• NMT 0.5%

• Medicine Name
• Bimatoprost

• Melting Point
• ~169C

• Molecular Formula
• C25H37NO4

• Molecular Weight
• 415.57 g/mol

• Particle Size
• NMT 10 microns

• Physical Form
• Solid

• Poisonous
• NO

• Purity(%)
• >99%

• Shelf Life
• 2 years

• Smell
• Other, Odorless

• Solubility
• Freely soluble in ethanol, slightly soluble in water

• Storage
• Other, Store at 2-8C, protected from light and moisture

• Structural Formula
• C25H37NO4

• Type
• Other, Active Pharmaceutical Ingredient

• Usage
• Used for the treatment of glaucoma and to promote eyelash growth

• Appearance
• White to off-white powder

• Boiling point
• Not applicable (decomposes before boiling)

• CAS No
• 70359-46-5

• Chemical Name
• 5-bromo-6-(2-imidazolidinylideneamino)quinoxaline tartrate

• Color
• Other, White to off-white

• EINECS No
• 274-492-3

• Grade
• Other, Pharmaceutical Grade

• HS Code
• 29334900

• Heavy Metal (%)
• 0.001%

• Loss on Drying
• 0.5%

• Medicine Name
• Brimonidine Tartrate API

• Melting Point
• 230-240C (decomposes)

• Molecular Formula
• C11H10BrN5.C4H6O6

• Molecular Weight
• 442.24 g/mol

• Particle Size
• 90% 10 microns

• Physical Form
• Powder

• Poisonous
• Other, No (for API use only, not for direct consumption)

• Purity(%)
• >= 99%

• Shelf Life
• 36 months when properly stored

• Smell
• Other, Odorless

• Solubility
• Freely soluble in water, slightly soluble in ethanol

• Storage
• Other, Store in a cool, dry place below 25C, protected from light

• Structural Formula
• Present as per standards (Available upon request)

• Type
• Other, Active Pharmaceutical Ingredient (API)

• Usage
• Used in the treatment of open-angle glaucoma and ocular hypertension

• Appearance
• Yellowish to orange powder

• CAS No
• 91714-93-1

• Chemical Name
• 2-amino-3-(4-bromobenzoyl)aniline

• Color
• Other, Yellow to orange

• EINECS No
• 691-732-6

• Grade
• Other, Pharmaceutical Grade

• HS Code
• 29333990

• Heavy Metal (%)
• NMT 0.001%

• Loss on Drying
• NMT 0.5%

• Medicine Name
• Bromfenac

• Melting Point
• 186-190C

• Molecular Formula
• C15H12BrNO3

• Molecular Weight
• 334.17 g/mol

• Particle Size
• NMT 10 micron

• Physical Form
• Powder

• Poisonous
• NO

• Purity(%)
• >99%

• Shelf Life
• 36 months

• Smell
• Other, Odorless

• Solubility
• Slightly soluble in water, soluble in organic solvents

• Storage
• Other, Store in a cool, dry place, protected from light

• Structural Formula
• C15H12BrNO3

• Type
• Other, Active Pharmaceutical Ingredient (API)

• Usage
• Used in the formulation of ophthalmic solutions for treatment of eye inflammation

• Appearance
• White to off-white powder

• CAS No
• 58551-69-2

• Chemical Name
• Carboprost Tromethamine

• Color
• Other, White to off-white

• EINECS No
• 261-082-2

• Grade
• Other, Pharmaceutical Grade

• HS Code
• 29375000

• Heavy Metal (%)
• Not more than 0.001%

• Loss on Drying
• Not more than 0.5%

• Medicine Name
• Carboprost

• Melting Point
• 107-112C

• Molecular Formula
• C25H47O8N

• Molecular Weight
• 489.64 g/mol

• Physical Form
• Powder

• Poisonous
• NO

• Purity(%)
• >=98% (by HPLC)

• Shelf Life
• 2 years when properly stored

• Smell
• Other, Odorless

• Solubility
• Freely soluble in water and methanol

• Storage
• Other, Store in a cool, dry place; protected from light and moisture

• Structural Formula
• Available on request

• Type
• Other, Active Pharmaceutical Ingredient

• Usage
• Used to treat postpartum hemorrhage and induce abortion

• Appearance
• White to off-white powder

• CAS No
• 23674-86-4

• Chemical Name
• Difluprednate

• Color
• Other, White to off-white

• EINECS No
• 245-735-7

• Grade
• Other, Pharmaceutical Grade

• HS Code
• 29372900

• Heavy Metal (%)
• 0.001%

• Loss on Drying
• 0.5%

• Medicine Name
• Difluprednate

• Melting Point
• 147C - 150C

• Molecular Formula
• C27H34F2O7

• Molecular Weight
• 508.55 g/mol

• Particle Size
• D90 10 m

• Physical Form
• Powder

• Poisonous
• NO

• Purity(%)
• >99%

• Shelf Life
• 36 months

• Smell
• Other, Odorless

• Solubility
• Sparingly soluble in ethanol and acetone, insoluble in water

• Storage
• Other, Store in a cool, dry place away from light and moisture

• Structural Formula
• Available on request

• Type
• Other, Active Pharmaceutical Ingredient (API)

• Usage
• For ophthalmic use; treatment of inflammation and pain associated with ocular surgery

• Appearance
• White to off-white powder

• CAS No
• 120279-96-1

• Chemical Name
• (4S,6S)-4-(ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-7,7-dioxide-2(3H)-one

• Color
• Other, White to off-white

• Grade
• Other, Pharmaceutical Grade

• HS Code
• 29349900

• Heavy Metal (%)
• 0.001%

• Loss on Drying
• 0.5%

• Medicine Name
• Dorzolomide

• Melting Point
• 256-260 C

• Molecular Formula
• C10H16N2O4S3

• Molecular Weight
• 324.44 g/mol

• Particle Size
• 90% < 10 microns

• Ph Level
• 5.0 - 7.0 (1% aqueous solution)

• Physical Form
• Solid

• Poisonous
• Other, Non-poisonous as API

• Purity(%)
• 99%

• Shelf Life
• 36 Months

• Smell
• Other, Odorless

• Solubility
• Slightly soluble in water, freely soluble in methanol

• Storage
• Other, Store in a cool, dry place, protected from light

• Structural Formula
• Available on request

• Taste
• Bitter

• Type
• Other, Active Pharmaceutical Ingredient (API)

• Usage
• Used in the formulation of Dorzolamide eye drops for the treatment of glaucoma and ocular hypertension

• Appearance
• White to off-white crystalline powder

• Boiling point
• Not applicable / decomposes

• CAS No
• 426-13-1

• Chemical Name
• Fluorometholone

• Color
• Other, White to off-white

• EINECS No
• 207-424-7

• Grade
• Other, Pharmaceutical Grade

• HS Code
• 29372900

• Heavy Metal (%)
• 0.001%

• Loss on Drying
• 0.5%

• Medicine Name
• Fluorometholone

• Melting Point
• 266-272C

• Molecular Formula
• C22H29FO4

• Molecular Weight
• 376.46 g/mol

• Particle Size
• 97% 10 micron

• Physical Form
• Solid

• Poisonous
• Other, Non-poisonous under recommended use

• Purity(%)
• >=99%

• Shelf Life
• 5 Years under recommended conditions

• Smell
• Other, Odorless

• Solubility
• Practically insoluble in water; soluble in acetone, methanol, and chloroform

• Storage
• Other, Store in a tightly closed container, in a cool, dry place

• Structural Formula
• Available upon request / see product documentation

• Taste
• Other , Tasteless

• Type
• Other, Active Pharmaceutical Ingredient (API)

• Usage
• Ophthalmic corticosteroid for anti-inflammatory purposes

• Appearance
• White to off-white powder

• CAS No
• 130209-82-4

• Chemical Name
• Latanoprost

• Color
• Other, White to off-white

• Grade
• Other, Pharmaceutical Grade

• HS Code
• 29322090

• Heavy Metal (%)
• 0.001%

• Loss on Drying
• 0.5%

• Medicine Name
• Latanoprost

• Melting Point
• ~75-77C

• Molecular Formula
• C26H40O5

• Molecular Weight
• 432.59 g/mol

• Particle Size
• NMT 10 microns

• Physical Form
• Solid

• Poisonous
• Other, Non-poisonous as an API (for pharmaceutical use only)

• Purity(%)
• 99%

• Shelf Life
• 2 years

• Smell
• Other, Odorless

• Solubility
• Soluble in organic solvents such as ethanol, methanol, and acetonitrile; practically insoluble in water

• Storage
• Other, Store at 2-8C, protected from light and moisture

• Structural Formula
• C26H40O5

• Type
• Other, Active Pharmaceutical Ingredient (API)

• Usage
• Used for the treatment of glaucoma and ocular hypertension

• Appearance
• White to off-white powder

• CAS No
• 82034-46-6

• Chemical Name
• Loteprednol Etabonate

• Color
• Other, White or almost white

• EINECS No
• 279-257-1

• Grade
• Other, Pharmaceutical Grade

• HS Code
• 29372900

• Heavy Metal (%)
• Not more than 0.001%

• Loss on Drying
• Not more than 0.5%

• Medicine Name
• Loteprednol Etabonate API

• Melting Point
• 197-199C

• Molecular Formula
• C24H31ClO7

• Molecular Weight
• 466.95 g/mol

• Particle Size
• D90 <10 Microns

• Physical Form
• Powder

• Poisonous
• NO

• Purity(%)
• >=99%

• Shelf Life
• 36 months

• Smell
• Other, Odorless

• Solubility
• Slightly soluble in water, soluble in ethanol and chloroform

• Storage
• Other, Store in a tightly closed container, protected from light, below 30C

• Structural Formula
• Available on request

• Type
• Other, Active Pharmaceutical Ingredient

• Usage
• Used in formulation of ophthalmic suspension and ointment for anti-inflammatory purposes

• Appearance
• White to off-white powder

• Boiling point
• Not applicable (decomposes before boiling)

• CAS No
• 186826-86-8

• Chemical Name
• Moxifloxacin Hydrochloride

• Color
• Other, White to pale yellow

• Grade
• Other, Pharmaceutical Grade

• HS Code
• 29419090

• Heavy Metal (%)
• 0.001%

• Loss on Drying
• 0.5%

• Medicine Name
• Moxifloxacin Active Pharmaceutical Ingredients

• Melting Point
• 235-245C

• Molecular Formula
• C21H24FN3O4HCl

• Molecular Weight
• 437.9 g/mol (as hydrochloride)

• Particle Size
• D90 <10 microns

• Ph Level
• 4.0 - 6.0 (1% aqueous solution)

• Physical Form
• Solid

• Poisonous
• Other, Non-poisonous under recommended conditions

• Purity(%)
• >=98.0%

• Shelf Life
• 36 months

• Smell
• Other, Odorless

• Solubility
• Soluble in water and methanol, slightly soluble in ethanol/acetone

• Storage
• Other, Store in a cool, dry, well-ventilated area, protected from light

• Structural Formula
• Available upon request / Refer to reference standard

• Taste
• Bitter

• Type
• Other, Antibiotic / Pharmaceutical Raw Material

• Usage
• Used for formulation of finished dosage forms; treatment of bacterial infections

• Appearance
• Off-white to pale yellow powder

• Boiling point
• Not applicable (decomposes before boiling)

• CAS No
• 78281-72-8

• Chemical Name
• Nepafenac

• Color
• Other, Off-white to pale yellow

• Grade
• Other, Pharmaceutical Grade

• HS Code
• 29420090

• Heavy Metal (%)
• <0.001%

• Loss on Drying
• 0.5%

• Medicine Name
• Nepafenac Micronised Sterile API

• Melting Point
• 191-193C

• Molecular Formula
• C15H14N2O2

• Molecular Weight
• 254.29 g/mol

• Particle Size
• Micronized; D90 <10 m

• Ph Level
• 5.0 - 7.5 (for 1% aqueous solution)

• Physical Form
• Powder

• Poisonous
• Other, Non-poisonous under recommended usage

• Purity(%)
• >=99% (by HPLC)

• Shelf Life
• 36 months from date of manufacture

• Smell
• Other, Odorless

• Solubility
• Practically insoluble in water, soluble in acetone and methanol

• Storage
• Other, Store in a cool, dry place, protected from light and moisture

• Structural Formula
• Provided on request or as per certificate of analysis

• Taste
• Other , Not applicable for API

• Type
• Other, API (Active Pharmaceutical Ingredient)

• Usage
• Used as a non-steroidal anti-inflammatory drug (NSAID) for ophthalmic preparations

• Appearance
• White or almost white crystalline powder

• Boiling point
• Not applicable (decomposes)

• CAS No
• 52-21-1

• Chemical Name
• Prednisolone 21-acetate

• Color
• Other, White to off-white

• EINECS No
• 200-134-1

• Grade
• Other, Pharmaceutical Grade

• HS Code
• 29372200

• Heavy Metal (%)
• 0.001%

• Loss on Drying
• 0.5%

• Medicine Name
• Prednisolone Acetate

• Melting Point
• 238-240C

• Molecular Formula
• C23H30O6

• Molecular Weight
• 402.48 g/mol

• Particle Size
• Micronized, 90% <10 microns

• Ph Level
• Neutral to slightly acidic (pH 5-7, in suspension)

• Physical Form
• Solid

• Poisonous
• Other, Non-poisonous at therapeutic dosages

• Purity(%)
• 99.0

• Shelf Life
• 5 years from manufacturing date if properly stored

• Smell
• Other, Odorless

• Solubility
• Very slightly soluble in water; freely soluble in chloroform, sparingly soluble in ethanol

• Storage
• Other, Store in a tightly closed container, protected from light and moisture, at 2-8C

• Structural Formula
• C23H30O6

• Taste
• Other , Slightly bitter

• Type
• Other, Active Pharmaceutical Ingredient (API)

• Usage
• Used in the manufacture of ophthalmic and systemic corticosteroid medications

• Appearance
• White to almost white crystalline powder

• Boiling point
• Not applicable (decomposes)

• CAS No
• 52-21-1

• Chemical Name
• Prednisolone 21-acetate

• Color
• White

• EINECS No
• 200-134-1

• Grade
• Other, Pharmaceutical Grade

• HS Code
• 29372900

• Heavy Metal (%)
• 0.001%

• Loss on Drying
• 0.5%

• Medicine Name
• Prednisolone Acetate Micronised Sterile API

• Melting Point
• 240-248C

• Molecular Formula
• C23H30O6

• Molecular Weight
• 402.48 g/mol

• Particle Size
• Micronized, typically D90 10 micron

• Ph Level
• Neutral

• Physical Form
• Powder

• Poisonous
• Other, No (for manufacturing use only, not for direct medicinal administration without formulation)

• Purity(%)
• 99.0% (by HPLC)

• Shelf Life
• 36 months from manufacture date (if unopened in original packaging)

• Smell
• Other, Odorless

• Solubility
• Practically insoluble in water; freely soluble in acetone, chloroform, and dioxane, slightly soluble in methanol

• Storage
• Other, Store in a tightly closed container, protected from light and moisture, at 2-8C

• Structural Formula
• C23H30O6 (structure available on request)

• Taste
• Other , Tasteless

• Type
• Other, Steroid corticosteroid API

• Usage
• Used in manufacturing ophthalmic and injectable dosage forms; for anti-inflammatory and immunosuppressive effects

• Appearance
• White to off-white powder

• Boiling point
• Not available/decomposes

• CAS No
• 209860-87-7

• Chemical Name
• Tafluprost

• Color
• Other, White to off-white

• Grade
• Other, Pharmaceutical Grade

• HS Code
• 29339900

• Heavy Metal (%)
• NMT 0.001%

• Loss on Drying
• NMT 0.5%

• Medicine Name
• Tafluprost

• Melting Point
• Approx. 68-72C

• Molecular Formula
• C25H34F2O5

• Molecular Weight
• 452.53 g/mol

• Particle Size
• NMT 10 m (as per requirement)

• Physical Form
• Solid

• Poisonous
• Other, No (handled as hazardous material)

• Purity(%)
• >=99%

• Shelf Life
• 24 months

• Smell
• Other, Odorless

• Solubility
• Soluble in organic solvents such as ethanol, DMSO

• Storage
• Other, Store at 2-8C, protect from light

• Structural Formula
• Provided on request

• Taste
• Other , Not determined

• Type
• Other, Active Pharmaceutical Ingredient (API)

• Usage
• Treatment of glaucoma and ocular hypertension

• Appearance
• White to off-white powder

• Boiling point
• Not available (decomposes)

• CAS No
• 157283-68-6

• Chemical Name
• Travoprost

• Color
• Other, White/Opaque

• EINECS No
• --

• Grade
• Other, Pharmaceutical Grade

• HS Code
• 29322090

• Heavy Metal (%)
• 0.001%

• Loss on Drying
• 0.5%

• Medicine Name
• Travoprost

• Melting Point
• 61-62C

• Molecular Formula
• C26H35F3O6

• Molecular Weight
• 500.55 g/mol

• Particle Size
• Micronized

• Physical Form
• Solid

• Poisonous
• NO

• Purity(%)
• 99%

• Shelf Life
• 24 months

• Smell
• Other, Odorless

• Solubility
• Soluble in organic solvents like ethanol and dichloromethane

• Storage
• Other, Store at 2-8C, protected from light

• Structural Formula
• Available on request

• Type
• Other, Active Pharmaceutical Ingredient

• Usage
• Glaucoma treatment, lowering intraocular pressure

• Appearance
• White to off-white crystalline powder

• Boiling point
• Not applicable (decomposes before boiling)

• CAS No
• 138890-62-7

• Chemical Name
• Brinzolamide

• Color
• Other, White to off-white

• Grade
• Other, Pharmaceutical Grade

• HS Code
• 29420090

• Heavy Metal (%)
• 0.001% (10 ppm)

• Loss on Drying
• 0.5%

• Medicine Name
• Brinzolomide

• Melting Point
• >120C (decomposes)

• Molecular Formula
• C12H21N3O5S3

• Molecular Weight
• 383.51 g/mol

• Particle Size
• Micronized; average particle size typically <10 microns

• Ph Level
• Not applicable (insoluble in water)

• Physical Form
• Solid

• Poisonous
• Other, No (when used as per prescription)

• Purity(%)
• >=99%

• Shelf Life
• 36 months

• Smell
• Other, Odorless

• Solubility
• Slightly soluble in methanol and ethanol, practically insoluble in water

• Storage
• Other, Store in a cool, dry, and well-ventilated place, protected from light

• Structural Formula
• Available on request

• Taste
• Bitter

• Type
• Other, Active Pharmaceutical Ingredient (API)

• Usage
• Used in the formulation of eye drops for the treatment of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma