Antimalarial API

• Appearance
• White to off-white crystalline powder

• CAS No
• 75847-73-3

• Chemical Name
• (R)-alpha-(2-Ethyl-1,3-dioxolan-2-yl) methyl artemether

• Color
• Other, White to off-white

• EINECS No
• 616-727-6

• Grade
• Other, Pharmaceutical Grade

• HS Code
• 29420090

• Heavy Metal (%)
• NMT 0.001%

• Loss on Drying
• NMT 0.5%

• Medicine Name
• Arteether

• Melting Point
• 86-88C

• Molecular Formula
• C17H28O5

• Molecular Weight
• 312.4 g/mol

• Particle Size
• NMT 10 micron

• Physical Form
• Solid

• Poisonous
• Other, Non-poisonous as API, but requires prescription

• Purity(%)
• > 99%

• Shelf Life
• 3 years

• Smell
• Other, Odourless

• Solubility
• Soluble in chloroform and ethanol, practically insoluble in water

• Storage
• Other, Store in a cool, dry, and well-ventilated place, away from light

• Structural Formula
• Available on request

• Taste
• Bitter

• Type
• Other, Active Pharmaceutical Ingredient (API)

• Usage
• Used for the treatment of severe malaria

• Appearance
• White to almost white crystalline powder

• Boiling point
• Decomposes before boiling

• CAS No
• 71963-77-4

• Chemical Name
• Artemether

• Color
• Other, White to off-white

• EINECS No
• 276-460-7

• Grade
• Other, Pharmaceutical Grade

• HS Code
• 29420090

• Heavy Metal (%)
• Not more than 0.001%

• Loss on Drying
• Not more than 0.5%

• Medicine Name
• Artemether

• Melting Point
• 86C - 88C

• Molecular Formula
• C16H26O5

• Molecular Weight
• 298.38 g/mol

• Particle Size
• 90% passing through 60 mesh

• Ph Level
• N/A (not applicable for solid API)

• Physical Form
• Solid

• Poisonous
• Other, Non-poisonous at therapeutic doses

• Purity(%)
• Not less than 99%

• Shelf Life
• 36 months

• Smell
• Other, Characteristic odor

• Solubility
• Practically insoluble in water, soluble in methanol and ethanol

• Storage
• Other, Store in a cool, dry place, protected from light and moisture

• Structural Formula
• C16H26O5 (displayed as skeletal structure in diagrams)

• Taste
• Bitter

• Type
• Other, Active Pharmaceutical Ingredient (API)

• Usage
• Used in the treatment of malaria

• Appearance
• White or almost white crystalline powder

• Boiling point
• Not applicable (decomposes)

• CAS No
• 88495-63-0

• Chemical Name
• Artesunate

• Color
• Other, White or off-white

• Grade
• Other, Pharmaceutical Grade

• HS Code
• 29420090

• Heavy Metal (%)
• 0.001%

• Loss on Drying
• 1.0%

• Medicine Name
• Artesunate Sterile API

• Melting Point
• 135C-140C

• Molecular Formula
• C19H28O8

• Molecular Weight
• 384.42 g/mol

• Particle Size
• D90 10 microns (customizable)

• Ph Level
• Neutral to slightly acidic (pH 5.5-6.5)

• Physical Form
• Powder

• Poisonous
• Other, Non-poisonous as raw material

• Purity(%)
• >=99%

• Shelf Life
• 3 years

• Smell
• Other, Odorless

• Solubility
• Slightly soluble in water, freely soluble in dichloromethane and methanol

• Storage
• Other, Store in a cool, dry and dark place, in tightly sealed containers

• Structural Formula
• Available on request

• Taste
• Bitter

• Type
• Other, Antimalarial Active Pharmaceutical Ingredient

• Usage
• Used for formulation of injectable and oral antimalarial medicines

• Appearance
• White to almost white, crystalline powder

• Boiling point
• Not applicable (decomposes)

• CAS No
• 50-63-5

• Chemical Name
• Chloroquine Phosphate

• Color
• White

• EINECS No
• 200-055-4

• Grade
• Other, Pharmaceutical Grade

• HS Code
• 2933.59.

• Heavy Metal (%)
• 0.001%

• Loss on Drying
• 6.0%

• Medicine Name
• Chloroquine Phosphate API

• Melting Point
• 167-172 C

• Molecular Formula
• C18H26ClN32H3PO4

• Molecular Weight
• 515.86 g/mol

• Particle Size
• 90% passes through 80 mesh

• Ph Level
• 4.0 - 5.5 (1% solution)

• Physical Form
• Solid

• Poisonous
• Other, Yes, in high doses

• Purity(%)
• >= 98.0%

• Shelf Life
• 36 months

• Smell
• Other, Odorless

• Solubility
• Freely soluble in water, slightly soluble in alcohol

• Storage
• Other, Store in tightly closed container at room temperature, protected from light and moisture.

• Structural Formula
• C18H26ClN32H3PO4

• Taste
• Bitter

• Type
• Other, Active Pharmaceutical Ingredient

• Usage
• Malaria treatment, anti-inflammatory, research purposes

• Appearance
• Clear to pale yellow, oily liquid

• CAS No
• 6217-54-5

• Chemical Name
• Docosahexaenoic Acid

• Color
• Other, Pale yellow

• EINECS No
• 228-672-0

• Grade
• Other, Pharmaceutical Grade

• HS Code
• 2936

• Heavy Metal (%)
• <0.001%

• Loss on Drying
• <0.5%

• Medicine Name
• DHA Active Pharmaceutical Ingredients

• Melting Point
• -44C

• Molecular Formula
• C22H32O2

• Molecular Weight
• 328.49 g/mol

• Particle Size
• NA (Liquid)

• Physical Form
• Liquid

• Poisonous
• Other, Non-poisonous

• Purity(%)
• >98%

• Shelf Life
• 24 months

• Smell
• Other, Characteristic, slight fish-like odor

• Solubility
• Insoluble in water, soluble in organic solvents

• Storage
• Other, Store in a cool, dry place, away from light and moisture

• Structural Formula
• C22H32O2

• Taste
• Other , Tasteless to slightly fishy

• Type
• Other, Active Pharmaceutical Ingredient

• Usage
• Pharmaceutical formulations, dietary supplements, clinical nutrition

• Appearance
• White to off-white crystalline powder

• Boiling point
• Not Applicable (decomposes)

• CAS No
• 747-36-4

• Chemical Name
• Hydroxychloroquine Sulfate

• Color
• Other, White or almost white

• EINECS No
• 212-017-2

• Grade
• Other, Pharmaceutical Grade

• HS Code
• 29334990

• Heavy Metal (%)
• 20 ppm

• Loss on Drying
• 0.5%

• Medicine Name
• Hydroxychloroquine

• Melting Point
• 240C - 243C

• Molecular Formula
• C18H26ClN3O.H2SO4

• Molecular Weight
• 433.95 g/mol

• Particle Size
• 90% passes through 80 mesh

• Ph Level
• 5.5 - 7.5 (1% solution)

• Physical Form
• Powder

• Poisonous
• Other, No (under prescribed usage)

• Purity(%)
• 99% min

• Shelf Life
• 5 years if properly stored

• Smell
• Other, Odorless

• Solubility
• Freely soluble in water and slightly soluble in alcohol

• Storage
• Other, Store in a cool, dry place and away from light

• Structural Formula
• (C18H26ClN3O)2H2SO4

• Taste
• Bitter

• Type
• Other, Active Pharmaceutical Ingredient (API)

• Usage
• Used for the treatment of malaria, rheumatoid arthritis, and lupus erythematosus

• Appearance
• Yellow crystalline powder

• CAS No
• 82186-77-4

• Chemical Name
• 2-(Dibutylamino)-1-[(9Z)-2,7-dichloro-9-(4-chlorobenzylidene)-9H-fluoren-4-yl]ethanol

• Color
• Yellow

• EINECS No
• 617-527-0

• Grade
• Other, Pharmaceutical Grade

• HS Code
• 29336990

• Heavy Metal (%)
• Not more than 0.001%

• Loss on Drying
• Not more than 0.5%

• Medicine Name
• Lumefantrine

• Melting Point
• 130-132C

• Molecular Formula
• C30H32Cl3NO

• Molecular Weight
• 528.94 g/mol

• Particle Size
• D90 < 10 microns (typical)

• Physical Form
• Solid

• Poisonous
• Other, Non-poisonous as a raw material, used under prescription only

• Purity(%)
• Not less than 98.0%

• Shelf Life
• 36 months

• Smell
• Other, Odorless

• Solubility
• Practically insoluble in water; soluble in dichloromethane, slightly soluble in acetonitrile

• Storage
• Other, Store in a cool, dry place, protected from light

• Structural Formula
• C30H32Cl3NO (as depicted in product documentation)

• Type
• Other, Active Pharmaceutical Ingredient (API)

• Usage
• Used in the treatment of malaria, typically in combination with artemether

• Appearance
• White to almost white crystalline powder

• Boiling point
• Decomposes

• CAS No
• 60-93-5

• Chemical Name
• Quinine Dihydrochloride

• Color
• White

• EINECS No
• 200-538-0

• Grade
• Other, Pharmaceutical Grade

• HS Code
• 29392020

• Heavy Metal (%)
• 0.001%

• Loss on Drying
• 1.0%

• Medicine Name
• Quinine Dihydrochloride API

• Melting Point
• 218 - 222 C

• Molecular Formula
• C20H24Cl2N2O2

• Molecular Weight
• 411.33 g/mol

• Particle Size
• Not less than 90% passes through 60 mesh sieve

• Ph Level
• 4.5 - 6.5 (1% solution)

• Physical Form
• Solid

• Poisonous
• Other, Yes, toxic in high doses

• Purity(%)
• >= 99%

• Shelf Life
• 3 years when properly stored

• Smell
• Other, Odorless

• Solubility
• Soluble in water, sparingly soluble in alcohol

• Storage
• Other, Store in a well-closed container, protected from light and moisture

• Structural Formula
• (Not shown, C20H24Cl2N2O2)

• Taste
• Other , Very bitter

• Type
• Other, Active Pharmaceutical Ingredient

• Usage
• Pharmaceutical formulation, antimalarial agent

• Appearance
• White crystalline powder

• Boiling point
• Not applicable (decomposes)

• CAS No
• 60-93-5

• Chemical Name
• Quinine Hydrochloride

• Color
• White

• EINECS No
• 200-508-1

• Grade
• Other, Pharmaceutical Grade

• HS Code
• 29392090

• Heavy Metal (%)
• 0.001%

• Loss on Drying
• 1.0%

• Medicine Name
• Quinine Hydrochloride API

• Melting Point
• 205C - 207C

• Molecular Formula
• C20H24N2O22HCl

• Molecular Weight
• 397.34 g/mol

• Particle Size
• Standard/Pharma grade mesh

• Ph Level
• 4.5 - 6.5 (1% solution)

• Physical Form
• Solid

• Poisonous
• Other, Yes (Toxic in large doses)

• Purity(%)
• 99%

• Shelf Life
• 5 years

• Smell
• Other, Odorless

• Solubility
• Freely soluble in water, sparingly soluble in alcohol

• Storage
• Other, Store in a cool, dry place away from light

• Structural Formula
• Displayed as per standard chemical structure

• Taste
• Other , Very bitter

• Type
• Other, API (Active Pharmaceutical Ingredient)

• Usage
• Antimalarial, pharmaceutical formulations

• Appearance
• White to almost white crystalline powder

• Boiling point
• Not applicable (decomposes)

• CAS No
• 6119-70-6

• Chemical Name
• Quinine Sulphate

• Color
• Other, White to off-white

• EINECS No
• 203-282-6

• Grade
• Other, Pharmaceutical Grade

• HS Code
• 29392000

• Heavy Metal (%)
• Not more than 0.001%

• Loss on Drying
• Not more than 0.5%

• Medicine Name
• Quinine Sulphate API

• Melting Point
• 218 - 223C

• Molecular Formula
• C20H24N2O2H2SO4

• Molecular Weight
• 782.96 g/mol

• Particle Size
• Micronized

• Ph Level
• 5.5 - 7.5 (1% solution)

• Physical Form
• Solid

• Poisonous
• Other, Yes (toxic in high doses)

• Purity(%)
• >= 98%

• Shelf Life
• 5 years if properly stored

• Smell
• Other, Odourless

• Solubility
• Slightly soluble in water; freely soluble in dilute acids

• Storage
• Other, Store in a cool, dry place, protected from light

• Structural Formula
• (C20H24N2O2)2H2SO4

• Taste
• Other , Very bitter

• Type
• Other, Active Pharmaceutical Ingredient (API)

• Usage
• Pharmaceutical preparations, Anti-malarial